A 2021 timeline
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Dr. Daniel Drucker receives 2021 Canada Gairdner International Award
Dr. Daniel Drucker is awarded the 2021 Canada Gairdner International Award, one of the most prestigious international prizes in the biosciences. Dr. Drucker, a senior investigator at LTRI, is part of a three-person team to be recognized for their research on glucagon-like peptides that led to major advances in the treatment of type 2 diabetes, obesity and intestinal disorders.
Innovative ultrasound technique enables earlier detection of placental diseases
Researchers have successfully taken their novel ultrasound technique from the bench to the bedside, demonstrating its effectiveness in detecting placental disease, which could ultimately help prevent some future stillbirths or serious illnesses in newborns. The study was co-led by Dr. John Kingdom, clinician scientist at LTRI and co-director of the Placenta Program at Mount Sinai Hospital.
Study recommends integrating placental growth factor blood testing for high-risk pregnancies
Dr. Kelsey McLaughlin, clinical research associate at Mount Sinai Hospital and LTRI, found a link between low circulating placental growth factor (PIGF) levels in high-risk pregnant women and adverse pregnancy outcomes.
LTRI scientists provide detailed map to understanding human cells
A team of researchers in the Gingras Lab at LTRI provided an ultra-detailed look at the organization of a living human cell, providing a new tool that can help scientists around the world better understand what happens during disease. The study was published in Nature.
Sinai Health research finds common denominator linking all cancers
All cancers fall into just two categories, according to research from LTRI senior scientist Rod Bremner. Published in Cancer Cell, his findings provide a new strategy for treating the most aggressive and untreatable forms of the disease.
New research shows sarcoma’s origins could be decades in the making
In a new study published in Nature Communications, scientists from Sinai Health and The Hospital for Sick Children (SickKids) provide an extensive look at the origins of leiomyosarcoma (LMS) and how it spreads and forms different genetic subtypes of LMS tumours.
Why a tiny worm’s brain development could shed light on human thinking
Researchers at Sinai Health have used a tiny worm to track how an animal’s brain changes throughout its lifetime, shedding new light on how human brains develop. Appearing in Nature, LTRI scientists describe four basic patterns of how new connections are made in the brain of the nematode worm, Caenorhabditis elegans, or C. elegans.
Study results show subtle differences in antibody response between Pfizer and Moderna vaccines for older people
A study by Drs. Anne-Claude Gingras and Allison McGeer reveals subtle differences between the immune responses of long-term care residents receiving the Pfizer-BioNTech or Moderna vaccines for COVID-19. The findings appeared in several major news media outlets, including CBC, the Globe and Mail and the New York Times.
The new AI tool that can sort millions of cells in minutes
Astir, a new tool designed by LTRI investigator Dr. Kieran Campbell, uses artificial intelligence to sort millions of cell types in the human body within minutes. As described in Cell Systems, scientists hope it could one day help doctors make faster diagnoses and treatment decisions.
dr. Daniel Durocher celebrated as pioneer in precision oncology medicine
As the saying goes, "It's an honour just to be nominated," and that's certainly the case for Dr. Daniel Durocher, who has successively taken basic science from bench to multi-million dollar company. Dr. Durocher was named as a finalist for the 2021 Bloom Burton Award, an honour that recognizes individuals who have made the greatest contribution to Canada’s innovative health-care industry. In 2016, Dr. Durocher founded Repare Therapeutics alongside another LTRI scientist, Dr. Frank Sicheri.
New biomarkers and cancer-driving genes found in the dark matter of the cancer genome
A new batch of prognostic cancer biomarkers have been discovered in an area where few have gone looking before. In a new study published in Cell Reports, Dr. Daniel Schramek describes using machine learning to evaluate 5,600 potential lncRNA biomarkers against nearly 9,500 cancer samples across 30 cancer types.
Hunting for the perfect rhythm to beat depression blues
When it comes to finding a long-lasting treatment for depression, LTRI scientists say it could come down to finding the perfect rhythm. Drs. Graham Collingridge and John Georgiou have received a grant from Brain Canada to further explore how altering the timing of pulses from transcranial magnetic stimulation, or TMS, could help patients with treatment-resistant depression.